Orthopedic Biologics
The DBM that stays.
The price that doesn't.
HSS-developed biologics trusted by top spine programs. 42% lower unit cost with handling that stays where you put it.
Trusted by leading spine programs
The Problem
Most hospital biologics budgets carry costs they don't need to.
- Premium pricing with no premium outcomes
- You're paying twice: once for the product, again when it washes out
- Inconsistent handling and unpredictable preparation
- Over-preparation and waste from limited sizing options
- No way to verify you're getting what you paid for
The Double Savings
Lower unit cost. Lower usage per case.
42% lower unit cost vs. major competitors — plus less product lost to irrigation means you use less per procedure. That's savings on savings.
$1,436
Saved per single-level
lumbar fusion
42%
Lower unit cost
vs. major competitors
$301,560 in annual savings per high-volume surgeon
Why 4D Biologics
Built for the OR. Priced for the institution.
Savings on Savings
42% lower unit cost — plus less product lost to irrigation means you use less per case.
It Just Stays Put
Consistent preparation. Predictable handling. No fragmentation. No washout.
Trusted by the Best
Developed at HSS. Used by Rothman, Jefferson, and Mount Sinai. Independent BMP-2 lot testing via Eurofins/VRL.
Right-Sized Units
Multiple sizing options reduce over-preparation and waste.
Our Portfolio
Everything You Need in the OR
Demineralized Bone Matrix
DBM
Putty, fibers, crush, cubes, and strips for fusion procedures. Consistent handling that stays where you put it.
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Cancellous Chips
Cancellous Chips
Mineralized allograft granules for scaffold extension around hardware and fusion sites.
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Synthetic Bone Graft
BioVive Synthetic
The only synthetic bone graft that mimics natural bone remodeling at the cellular level.
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dHAM
Amnion
Dual-layer surgical covering. Chorion-free. Either-side placement. Sized 1×1 to 4×8 cm.
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Placental Membrane
4D Flakes
Shelf-stable placental membrane for healing support. Room temperature storage. 3-year shelf life.
Learn MoreSurgeon Feedback
What Surgeons Say
“4D Biologix's demineralized bone matrix has become a cornerstone adjunct in my fusion procedures because of its consistency, structural integrity, and dependable biologic performance.”
“OsteoBlend has been part of the winning formula for my complicated spinal fusion surgeries... I give OsteoBlend my full endorsement.”
“Unlike many DBM products that may become excessively friable or susceptible to washout, this material remains stable at the surgical site... resulting in shortened operative times.”
Who We Serve
Two audiences. One mission.
For Surgeons
Performance you can feel in the OR
- Consistent handling — stays where you put it
- No washout during irrigation
- Independent BMP-2 lot testing
- Multiple forms and sizing options
For Institutions
From VAC to OR in 30 days
- Side-by-side cost analysis against your current biologics spend
- No retraining required — same product categories your surgeons already use
- Flexible trial programs with select surgeons before full conversion
- Dedicated implementation support from first case through contract
Next Steps
See Your Savings
Request a Cost Analysis
We'll compare your current biologics spend against 4D pricing.
Schedule a Demo
See the handling characteristics firsthand.
Start a Trial
Low-risk pilot with select surgeons.