Clinical Evidence
Research-Backed Performance
Independent testing. Documented outcomes. Transparent data.
Quality Assurance
Independent Lot Testing
Every lot of 4D Biologix DBM undergoes independent testing to verify biologic activity. Results are verifiable and auditable — giving your VAC and surgical team confidence in every unit.
- Conducted by Eurofins/VRL — independent third-party lab
- Quantikine BMP-2 EIA assay methodology
- Reports BMP-2 concentration (pg/g DBM) per lot
- Verifiable and auditable results available on request
Every Lot. Every Time.
Independent BMP-2 testing via Eurofins/VRL using the Quantikine assay — the gold standard in biologic activity verification.
Institutional Trust
Trusted by Leading Institutions
Hospital for Special Surgery
Product development origin. Consistently ranked #1 in orthopedics.
Rothman Orthopaedic Institute
Leading spine and orthopedic program.
Thomas Jefferson University Hospital
Academic medical center of excellence.
Mount Sinai
Major health system adoption.
Surgeon Feedback
What Surgeons Say
“4D Biologix's demineralized bone matrix has become a cornerstone adjunct in my fusion procedures because of its consistency, structural integrity, and dependable biologic performance.”
“OsteoBlend has been part of the winning formula for my complicated spinal fusion surgeries... I give OsteoBlend my full endorsement.”
“Unlike many DBM products that may become excessively friable or susceptible to washout, this material remains stable at the surgical site... resulting in shortened operative times.”
Next Steps
See Your Savings
Request a Cost Analysis
We'll compare your current biologics spend against 4D pricing.
Schedule a Demo
See the handling characteristics firsthand.
Start a Trial
Low-risk pilot with select surgeons.